Work

Anemia of Chronic Disease and Chronic Periodontitis: Estimation of Hematological Status and its Correlation with Clinical Parameters

Year: 2024

Type: article

Abstract: Periodontitis is an inflammatory disease of the supporting tissues of the tooth caused by specific bacteria in a susceptible host.Lainson stated that anemia is a systemic cause of periodontitis.While leukocytosis is a common feature of severe periodontitis, a smaller amount of evidence has been produced on erythrocyte counts in periodontitis, suggesting a possible tendency to develop anemia.The present study was carried out with a view to investigate the associations and estimation of the hematological status and its correlation with the clinical parameters between periodontitis and the Hematocrit, Hb, MCV, MCH, MCHC, TLC, Differential WBC count, Platelet count, BT and CT. AimTo evaluate levels of hematological parameters in healthy and chronic periodontitis patients. MethodologyThe parameters assessed were the hematocrit, hemoglobin (Hb), MCV (Mean Corpuscular Volume), MCH (Mean Corpuscular Hemoglobin), MCHC (Mean Corpuscular Hemoglobin Concentration), Total Leucocyte count (TLC), Differential WBC count, Platelet count, Bleeding time (BT) and Clotting time (CT) will be measured. ResultThe decrease in the hematocrit and Hb with mean gingival index, mean plaque index, leukocytosis, thrombocytosis was significantly higher in periodontitis patients than in the healthy group and were statistically significant.Differential WBC Count showed a MCV was slightly lower in the periodontitis group while MCH, MCHC, BT and CT were also known to affect but were not statistically significant.There is no significant correlation between GI, CAL, BOP, MCHC.No statistically significant correlation exists between PPD changes and hematological factors associated with anemia. ConclusionThe authors conclude that the patients suffering from untreated chronic periodontitis often suffer from anemia of chronic disease with marked leucocytosis and reactive thrombocytosis.

Source: Journal Of Oral Medicine And Dental Research

DOI: 10.52793/jomdr.2024.5(3)-64

Author: Sharayu Dhande

Institution: Sinhgad Dental College and Hospital

Language: English

Topic: Oral microbiology and periodontitis research

Subfield: Periodontics

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4402733487