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Figure S4 from BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer

Year: 2024

Type: other

Abstract: (A) qPCR analysis of Wnt inhibitors Dkk1, Notum, and Axin2 in ID8 mouse ovarian cancer cells. Data are presented as mean +/- SEM (n=3). Ordinary one-way ANOVA with Dunnett’s multiple comparison test was used to calculate statistical significance; (B) Western blot analysis validates upregulation of Axin2 upon loss of BRCA2.

DOI: 10.1158/2767-9764.27087807.v1

Authors: Hussein Chehade, Radhika Gogoi, Nicholas K. Adzibolosu, Sandra Galoforo, Rouba-Ali Fehmi, Mira Kheil, Alexandra Fox, Seongho Kim, Ramandeep Rattan, Zhanjun Hou, Robert T. Morris, Larry H. Matherly, Gil Mor, Ayesha B. Alvero

Language: English

Topic: Wnt/β-catenin signaling in development and cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4402750106

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