Work

Evaluating the halogen bonding strength of a iodoloisoxazolium(III) salt

Year: 2024

Type: article

Abstract: Diaryliodonium(III) salts have been established as powerful halogen-bond donors in recent years. Herein, a new structural motif for this compound class was developed: iodoloisoxazolium salts, bearing a cyclic five-membered iodolium core fused with an isoxazole ring. A derivative of this class was synthesized and investigated in the solid state by X-ray crystallography. Finally, the potential as halogen-bonding activator was benchmarked in solution in the gold-catalyzed cyclization of a propargyl amide.

Source: Beilstein Journal of Organic Chemistry

DOI: 10.3762/bjoc.20.204

Authors: Dominik L Reinhard, Anna Schmidt, Marc Sons, Julian Wolf, Elric Engelage, Stefan M Huber

Institution: Ruhr University Bochum

Language: English

Topic: Crystallography and molecular interactions

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

Funders: Fonds der Chemischen Industrie, Deutsche Forschungsgemeinschaft

Awards: EXC 2033: RESOLV (Ruhr Explores Solvation), G199205490, G274347230, G649001848