Work

Four Cases of Single-Fraction Stereotactic Body Radiation Therapy for Prostate Cancer

Year: 2024

Type: article

Abstract: Hypofractionated radiotherapy for prostate cancer has been reported to date. Here, we report on four patients with prostate cancer who were treated with single-fraction stereotactic body radiation therapy. It was conducted with reference to some previous clinical trials. The median age of the patients was 76.5 years (range: 72-89 years). All except one patient with low-risk prostate cancer received androgen deprivation therapy (ADT) before irradiation. All patients received a dose of 24 Gy in one fraction using X-ray photon beams when prostate-specific antigen (PSA) fell to low levels due to ADT. After irradiation, all patients had a gradual decline in PSA, and so far none has had a PSA recurrence. Although Grade 1-2 adverse events occurred in all cases, none of the patients showed adverse events of Grade 3 or over during the observation period.

Source: Cureus

DOI: 10.7759/cureus.70062

Authors: Ayane Yasui, Subaru Sawayanagi, Yuki Nozawa, Daichi Sugahara, Hideomi Yamashita

Institutions: University of Tokyo Hospital, The University of Tokyo

Language: English

Topic: Prostate Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402782282