Cryochemical Synthesis of Hybrid Nanoforms Based on Silver and the Antibacterial Drug Substance Dioxidine
Year: 2024
Type: article
Abstract: Hybrid nanoforms based on silver and antibacterial drug dioxidine (2,3-bis-(hydroxymethyl)quinoxaline 1,4-di-N-oxide) were prepared by the method of joint co-condensation of metal and ligand vapors on a liquid nitrogen cooled surface. The samples obtained by low temperature co-condensation were characterized by FTIR-, UV-Vis and XPS-spectroscopy, ТЕМ, SEM and powder X-ray phase analysis (ХРА). It was shown that cryomodified nanoforms preferably consist of anhydrous triclinic (T-phase) crystal phase of dioxidine, the dimensions of dioxidine particles ranges from 50 to 300 nm, the average size of included silver nanoparticles is (15±3) nm. Broadening of the diffraction patterns belonging to silver shows the transition of metallic silver to the nanoscale state. The FTIR results indicate for hybrid nanoforms stabilized by donor-acceptor interactions of surface silver atoms with hydroxyl groups and with donor N-atoms of quinoxaline cycles of dioxidine molecules.
Source: Lomonosov chemistry journal
Authors: ANDREY V. SOLOVIEV, SOFIA A. GROMOVA, YANA A. GROMOVA, ANDREY V. SHABATIN, YURII N. MOROSOV, TATYANA I. SHABATINA
Language: English
Field: Materials Science
Domain: Physical Sciences
Open Access status: bronze
OpenAlex ID: W4402802772