Work

Impact of obesity on clinical outcomes of methicillin-susceptible Staphylococcus aureus bloodstream infections

Year: 2024

Type: article

Abstract: ABSTRACT Obesity affects over one-third of U.S. adults and complicates the treatment of methicillin-susceptible Staphylococcus aureus (MSSA) bloodstream infections (BSI). A study at the University of Florida Health Centers compared clinical outcomes between 233 obese and non-obese patients receiving cefazolin for MSSA BSI. No significant differences were found in clinical success (81.9% vs 82.7%), mortality (7.2% vs 5.3%), or adverse events (3.6% vs 3.3%). However, obese patients took longer to clear blood cultures (4.62 vs 4.01 days, P = 0.017).

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00752-24

Authors: Anthony S. Wasielewski, Anthony M. Casapao, Christopher A. Jankowski, Carmen L. Isache, Malleswari Ravi, Ashlan J. Kunz Coyne

Institutions: University of Florida Health, University of Florida Health Science Center, University of Florida

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4402863855