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Eosinophilic Granulomatous Interstitial Nephritis in Eosinophilic Granulomatous Polyangiitis

Year: 2024

Type: article

Abstract: A 74-year-old woman with bronchial asthma and schizophrenia was admitted to our hospital with leg numbness and eosinophilia.Laboratory tests revealed the following: eosinophils, 11,840/μL; creatinine (Cr), 0.78 mg/dL; urinary protein/Cr ratio, 0.77 g/gCr without hematuria; and urinary β2microglobulin, 83,900 μg/L.Myeloperoxidase and proteinase 3 antineutrophil cytoplasmic antibody tests were negative.Computed tomography revealed ground-glass opacities in both lungs, and magnetic resonance imaging (T2-weighted imaging) revealed high-intensity lesions in the left ventricular anterior wall and septum.A renal biopsy revealed eosinophilic infiltrates (arrowheads, Picture 1) and non-

Source: Internal Medicine

DOI: 10.2169/internalmedicine.4274-24

Authors: Machi Kiyohara, Tokio Katakura, Yuki Nakamura, Izaya Nakaya

Institution: Iwate Prefectural Central Hospital

Language: English

Topic: Eosinophilic Disorders and Syndromes

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402884634

FWCI:

Cites: 2

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Related to: 10