Year: 2024
Type: article
Abstract: and inflammation are major functions of NK cells [1].They consist of various heterogeneous subpopulations, each with distinct immunophenotypes and functions [2-4].Bright or dim CD56 expression, with or without CD16 expression, is immunophenotypically the hallmark of NK cells, as well as the variable expression levels of CD94-NKG2 heterodimers, members of the killer immunoglobulin-like receptor (KIR) family, and members of the natural cytotoxicity receptor (NCR) family.Classically, NK cells are classified into immature (CD56 bright , CD94 hi , CD16 -, CD57 -), mature (CD-56 dim-to-med , CD94 med , CD16 + , CD57 -), and hypermature (CD56 dim-to- med , CD94 low , CD16 + , CD57 + ) based on their expression levels of CD16, CD56, CD57, and CD94 [2, 3].Through recent studies, the diversity of NK cell subpopulations has been expanded to a remarkable degree [5, 6].Cytometry by time-of-flight (CyTOF) analyses assessing 37 parameters simultaneously have unveiled the immense diversity within NK cell subpopulations, identifying up 자연살해세포의 특성을 보유한 특이한 CD56 + CD19 dim 세포 Unusual CD56 + CD19 dim Cells with Natural Killer Cell Characteristics
Source: Laboratory Medicine Online
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W4402886681