Scanning Probe Nano‐Infrared Imaging and Spectroscopy of Biochemical and Natural Materials
Year: 2024
Type: article
Abstract: The mid-infrared with a characteristic wavelength of 3-20 μm is important for a wealth of technologies. In particular, mid-infrared spectroscopy can reveal material composition and structure information by fingerprinting chemical bonds' infrared resonances. Despite these merits, state-of-the-art mid-infrared techniques are spatially limited above tens of micrometers due to the fundamental diffraction law. Herein, recent progress in the scanning probe nanoscale infrared characterization of biochemical materials and natural specimens beyond this spatial limitation is reviewed. By leveraging the strong tip-sample local interactions, scanning probe nano-infrared methods probe nanoscale optical and mechanical responses to disclose material composition, heterogeneity, orientation, fine structure, and phase transitions at unprecedented length scales. These advances, therefore, revolutionize the understanding of a broad range of biochemical and natural materials and offer new material manipulation and engineering opportunities close to the ultimate length scales of fundamental physical, chemical, and biological processes.
Source: Small Science
Institution: Auburn University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $5,770
Awards: CAREER: Nano-Plasmon Ruler Imaging for Direct Visualization of How Cells "Talk", RII Track-4: van der Waals polaritonics for mid-infrared light emitters, CAREER: vdW isotope heterostructuring showcased in phononic light-matter interactions, G8696232870, Machine Learning-Assisted Integrated Optofluidic Nanoplasmonic Biosensing for Precision Immune Profiling and Monitoring
OpenAlex ID: W4402899585