Year: 2024
Type: article
Abstract: Sickle cell disease (SCD) is a hereditary haemoglobinopathy which causes multi-organ dysfunction. Pregnancies in SCD are high risk with significant maternal and fetal morbidity and mortality, including vaso-occlusive crises, thrombosis, anaemia, placental insufficiency, fetal growth restriction, preterm birth and medication effects. High level evidence on this topic is lacking. The Australian Sickle Cell Disease Working Group has reviewed international guidelines on this topic and provide an up-to-date and structured approach to the pre-conception, antenatal, birth and post-partum management of these women. Early and comprehensive multidisciplinary care involving experienced clinicians is recommended.
DOI: 10.1111/ajo.13888
Institutions: Mater Health Services, The University of Queensland, The Royal Melbourne Hospital, The University of Melbourne, Peter MacCallum Cancer Centre, Royal Women's Hospital, Monash Health, Monash University, Royal Hospital for Women, UNSW Sydney, Prince of Wales Hospital, NSW Health Pathology
Language: English
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,730
Funder: University of New South Wales
OpenAlex ID: W4402909014