Work

Emergence and stability of endoplasmic reticulum network streaming in plant cells

Year: 2024

Type: article

Abstract: The endoplasmic reticulum (ER) network is highly complex and highly dynamic in its geometry, and undergoes extensive remodeling and bulk flow. It is known that the ER dynamics are driven by actin–myosin dependent processes. ER motion through the cytoplasm will cause forces on the cytoplasm that will induce flow. However, ER will also clearly be passively transported by the bulk cytoplasmic streaming. We take the complex ER network structure into account and propose a positive-feedback mechanism among myosin-like motors, actin alignment, ER network dynamics for the emergence of ER flow. Using this model, we demonstrate that ER streaming may be an emergent feature of this three-way interaction and that the persistent-point density may be a key driver of the emergence of ER streaming. • Endoplasmic reticulum (ER) streaming is a key bulk transport process in plant cells. • This streaming is interrelated to cytoplasmic flow, the ER network and actin–myosin processes. • We investigate the emergence of ER streaming through interaction of myosin-like motors, actin alignment, and ER network dynamics.

Source: Journal of Theoretical Biology

DOI: 10.1016/j.jtbi.2024.111954

Authors: Graham M. Donovan, Congping Lin, Imogen Sparkes, Peter Ashwin

Institutions: University of Auckland, Huazhong University of Science and Technology, University of Bristol, University of Exeter

Language: English

Topic: Cellular transport and secretion

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $2,450

Funders: National Natural Science Foundation of China, Engineering and Physical Sciences Research Council