Before blaming glucocorticoids for prolonged postoperative hypotension, alternative explanations must be carefully ruled out
Year: 2024
Type: article
Abstract: We read with interest the article by Sharma and Venkatapura on a 9-year-old girl with an extra-axial mass lesion along the vermis who suffered persistent arterial hypotension intraoperatively.[3] e intraoperative hypotension was attributed to suppression of the hypothalamic-pituitary-adrenal (HPA) axis, as only hydrocortisone was effective.[3] It was concluded that resistant perioperative hypotension can occur not only with chronic steroid use but also after a single high dose of steroids and that risk factors for HPA suppression after steroid administration include cumulative duration of use, long-acting agents, and parenteral administration.[3] e study is excellent, but some points should be discussed.www.surgicalneurologyint.
Source: Surgical Neurology International
Author: Josef Finsterer
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402931787