Year: 2024
Type: article
Abstract: Nano-tribology focuses on the phenomena of friction, wear and lubrication at nano-scale, while biomechanics studies the response of objects and biomaterials under mechanical load. Through theoretical analysis, experimental operation and numerical simulation, this study comprehensively discusses the influence of siphon phenomenon on tribology and biomechanics at nanometer scale. Gold nanoparticles, silica nanoparticles and polymer nanoparticles were selected in the experiment. HeLa cells and primary cells were taken as biological samples, and the friction between nanoparticles and cells and the elastic modulus of cell membrane were quantified by using high-precision equipment such as atomic force microscope (AFM) and nano-indentation instrument. The results show that the siphon phenomenon significantly enhances the friction between nanoparticles and cell membrane under high humidity, and the increase of friction is positively correlated with the elastic modulus of cell membrane. It is found that the friction between gold nanoparticles and cells is generally higher than that between silica and polymer nanoparticles under the same humidity, which may be related to the physical and chemical properties of nanoparticles. This study not only reveals the close coupling relationship between nano-tribology and biomechanics, but also provides theoretical basis and experimental reference for the application of nano-biomedicine.
DOI: 10.62051/qjr0z463
Author: Jiabao Jia
Institution: Shandong Normal University
Language: English
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4402937192