Exploring the Antidiabetic Activities of Murraya Koenigii, Aegle Marmelos and Laurus nobilis: An In Vitro Study
Year: 2024
Type: article
Abstract: Aim and Objective: This study investigates the antidiabetic properties of Murraya koenigii (curry leaf), Aegle marmelos (bael) and Laurus nobilis (bay leaf) using in vitro assays. The plants have been traditionally used in Indian medicinal systems for the treatment of diabetes and other disorders. Methodology: Hydroalcoholic extracts from the leaves of Murraya koenigii, Laurus nobilis and fruit pulp of Aegle marmelos were evaluated for their ability to inhibit key enzymes, ? - glucosidase and ? - amylase, involved in diabetes management. The studies were performed in vitro using enzyme substrates and plant extracts. Results & Conclusion: The results suggest that all the plants exhibit significant antidiabetic activities. But strongest antidiabetic properties were exhibited by Murraya koenigii leaf extracts followed by pulp of Aegle marmelos. The minimum antidiabetic activity was reported by Laurus nobilis leaf extract. These results support their use in traditional medicine and potential development into therapeutic agents. As a result, the study's significant findings demonstrate that it is a step towards evidence - based phytomedicine.
Authors: Nupur Sinha, Rahul E
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4402939355