Work

Hemodynamics study of anterior cerebral artery with different sac centerline lengths for rupture risk assessment

Year: 2024

Type: article

Abstract: The present research extensively investigates the significance of the sac centerline length of the anterior cerebral artery (ACA) on aneurysm rupture risk. Hemodynamic factors influencing aneurysm rupture are assessed to identify critical regions prone to rupture. Wall shear stress is analyzed by modeling blood flow in three real saccular ACA cases with varying sac centerline lengths. A one-way fluid-solid interaction (FSI) model is employed to examine the interaction between blood flow and vessel deformation. The computational study reveals that wall shear stress on the ACA saccular aneurysm wall is significantly higher when the sac centerline length is shorter. Conversely, the mean oscillatory index changes with different sac centerline lengths, showing that an increase in sac centerline length leads to higher blood oscillation within the sac area in ACA cases.

Source: Scientific Reports

DOI: 10.1038/s41598-024-73231-z

Authors: Zhenjin Su, Weiyan Teng, Yanhua Liu, Hengtong Wan, Zeshang Guo

Institutions: Jilin University, First Hospital of Jilin University, First Bethune Hospital of Jilin University

Language: English

Topic: Intracranial Aneurysms: Treatment and Complications

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,590