Measurement of emerging neurocognitive and language skills in the HEALthy Brain and Child Development (HBCD) study
Year: 2024
Type: article
Study design: Study Protocol
Abstract: The HEALthy Brain and Child Development (HBCD) study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The study plans enrolling over 7000 families across 27 sites. This manuscript presents the measures from the Neurocognition and Language Workgroup. Constructs were selected for their importance in normative development, evidence for altered trajectories associated with environmental influences, and predictive validity for child outcomes. Evaluation of measures considered psychometric properties, brevity, and developmental and cultural appropriateness. Both performance measures and caregiver report were used wherever possible. A balance of norm-referenced global measures of development (e.g., Bayley Scales of Infant Development-4) and more specific laboratory measures (e.g., deferred imitation) are included in the HBCD study battery. Domains of assessment include sensory processing, visual-spatial reasoning, expressive and receptive language, executive function, memory, numeracy, adaptive behavior, and neuromotor. Strategies for staff training and quality control procedures, as well as anticipated measures to be added as the cohort ages, are reviewed. The HBCD study presents a unique opportunity to examine early brain and neurodevelopment in young children through a lens that accounts for prenatal exposures, health and socio-economic disparities. • Details of the neurocognitive and language battery of the HBCD study are outlined. • Repeated assessments using caregiver reports and direct observations are used in HBCD. • HBCD neurocognitive and language assessments will be conducted in English and Spanish. • Extensive training of diverse, bilingual research assistants was conducted. • Alignments with other large-scale studies, such as ABCD, are discussed.
Authors: Julie A. Kable, Alexandra S. Potter, Natacha Akshoomoff, Patricia M. Blasco, Stefanie C. Bodison, Lucia Ciciolla, Sherry DeGray, Zoe Hulce, Emily S. Kuschner, Britley Learnard, Monica Luciana, Alexandra Perez, Miriam A. Novack, Tracy Riggins, So Yeon Shin, Sidney Smith, Jennifer Vannest, Eric.H. Zimak
Institutions: Emory University, University of Vermont, University of California San Diego, Oregon Health & Science University, University of Florida Health, University of Florida, Oklahoma State University, Children's Hospital of Philadelphia, University of Pennsylvania, University of Minnesota, Northwestern University, University of Maryland, College Park, Cincinnati Children's Hospital Medical Center, University of Cincinnati, University of New Mexico, University of New Mexico Health Sciences Center
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,440
Funders: U.S. Department of Health and Human Services, University of North Carolina, National Institutes of Health, University of California, Los Angeles, National Institute on Drug Abuse, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G1101846420, G1140962045, G1436251778, G1465552184, G2073895022, G2101141570, G2240001569, G268108513, G2916529542, G3114796814, G3312042162, G383857204, G398914654, G4073742324, G4416667868, G4771492115, G478247456, G5159173176, G8281824583, G9000001406, G9000018615, G9000070839, G9000077204, G9000090994, G9000121524, G9000134307, G9000185846, G9000187175, G9000238887, G9000243320, G9000249646, G9000271934, G9000318151, G9000318253, G9000347086, 17/24 Healthy Brain and Child Development National Consortium, 4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium, 12/24 Healthy Brain and Child Development National Consortium, 6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium Vanderbilt, 10/24 Healthy Brain and Child Development National Consortium, 5/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium, 9/24- Healthy Brain and Child Development National Consortium, 13/24 The Healthy Brain and Child Development National Consortium, 18/24 Healthy Brain and Child Development National Consortium, 1/24 Healthy Brain and Child Development National Consortium, 3/24 Healthy Brain and Child Development National Consortium, G927754815
OpenAlex ID: W4402945262