Work

Direct extension from primary tumour to nodes: Can molecular profiling solve the dilemma?

Year: 2024

Type: article

Abstract: • Extranodal extension determines the prognosis and post-operative treatment of head and neck cancer patients. • Direct tumour invasion to nodes, metastasis with extranodal extension, & capsular invasion can present similar histology. • Molecular profiling, particularly the analysis of tumour heterogeneity, hold a great promise in solving the dilemma. • Combining molecular analysis with clinical & histological data could enhance diagnostic accuracy of these three scenarios.

Source: Oral Oncology Reports

DOI: 10.1016/j.oor.2024.100664

Authors: Gargi Sarode, Dheeraj Meena, Sayali Tungikar, Atharv Shrotri, Sachin Sarode

Institutions: Dr. D.Y. Patil Vidyapeeth, Pune, Dr D Y Patil Dental College & Hospital

Language: English

Topic: Head and Neck Cancer Studies

Subfield: Otorhinolaryngology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,100