Year: 2024
Type: article
Abstract: Introduction. Platelets can interact directly with viruses, bacteria, fungi and protozoa through proteins with direct microbicidal properties that can generate an antimicrobial effect in burns. Objective. To characterize the antimicrobial effect of platelet lysate in the treatment of burn patients. Methods. Observational, descriptive, prospective longitudinal study in patients with type A and AB dermal burns, with less than 5% of the body surface burned. Platelet concentrate production was performed using internationally established methods. Microbiological study was performed before and after the cures with platelet lysate and bacterial growth was evaluated in two subsequent cultures. Results. The mean age of the patients is 52 years and type AB burns represented 75% of the total, being more frequent in upper and lower limbs. Staphylococcus aureus and pseudomona aeruginosa were the predominant germs that grew in the burns. After the first treatment with platelet lysate, a gradual decrease in positivity to germs was observed, until in the third treatment, no more bacterial growth was observed. Conclusions. Platelet lysate has a positive antimicrobial effect, by decreasing the growth of germs isolated during the treatment of dermal burns.
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4402947459