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Acute Respiratory Distress Syndrome After Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) Vaccination: Findings From an Autopsy

Year: 2024

Type: article

Abstract: A male patient in his 80s was brought to our emergency room with a one-day history of general malaise and cough. He had received a severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination seven days earlier. He initially presented with respiratory failure, and an alveolar hemorrhage was suspected. The patient was intubated and admitted to the intensive care unit. We suspected that the alveolar hemorrhage was caused by acute respiratory distress syndrome (ARDS). Treatment including high-dose corticosteroid therapy and venovenous extracorporeal membrane oxygenation (ECMO) was initiated, however, the patient did not respond to treatment and died 35 days after admission. Pathological autopsy revealed diffuse alveolar damage (DAD) and idiopathic diffuse alveolar hemorrhage (DAH) consistent with ARDS. ARDS should be considered as a differential diagnosis when a patient develops respiratory symptoms after receiving the SARS-CoV-2 vaccine.

Source: Cureus

DOI: 10.7759/cureus.70370

Authors: Fumiya Kawano, Mikiya Kato, Yasuaki Tsuchida, Jumpei Okawa, Hideki Arimoto

Institution: Nippon Medical School Hospital

Language: English

Topic: COVID-19 Clinical Research Studies

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402949823