A long-term high-fat diet induces differential gene expression changes in spatially distinct adipose tissue of male mice
Year: 2024
Type: article
Abstract: A long-term high-fat diet induced the expression of more than 980 unique genes across subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). The high-fat diet also induced the differential expression of nearly 1,000 AT genes. We identified four genes that were oppositely expressed in SAT versus VAT in response to the high-fat diet and propose that these genes in particular may serve as promising targets aimed at resolving VAT dysfunction in obesity.
Source: Physiological Genomics
Authors: Malak Alradi, Hassan Askari, Mark Shaw, Jaysheel D. Bhavsar, Brewster F. Kingham, Shawn W. Polson, Ibra S. Fancher
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402977663