Work

Antimicrobial Activity of Terpenes and Oxygen-Containing Terpenoids Against Staphylococcus aureus

Year: 2024

Type: article

Abstract: At various pathological states, Staphylococcus aureus may cause a number of diseases. Rapid spread of antibiotic resistance necessitates the search for alternative approaches to antimicrobial treatment of staphylococci. Due to their membranotropic properties, natural and synthetic terpenoids are capable both of antimicrobial action and of potentiation of the effect of other antimicrobial agents. Antimicrobial activity of 53 natural terpenes and their synthetic oxygen-containing derivatives was determined, as well as their ability to potentiate the effect of known antimicrobials on S. aureus. Two- to fourfold increase in efficiency of amikacin, ceftriaxone, and miramistin in the presence of (+)-3β,4β-carandiol and (‒)-myrtenic acid indicates the possibility of their application for combined therapy together with medical preparations in order to decrease the concentrations of the latter.

Source: Микробиология

DOI: 10.31857/s0026365624030167

Authors: A. I. Kolesnikova, A. R. Kayumov, I. R. Gilfanov, L. L. Frolova, L. E. Nikitina, E. Yu. Trizna

Institutions: Kazan Federal University, Russian Academy of Sciences, Ural Branch of the Russian Academy of Sciences, Institute of Chemistry, Komi Science Center, Kazan State Medical University

Language: English

Topic: Essential Oils and Antimicrobial Activity

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4402983740

FWCI:

Cites: 16

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Related to: 10