Rudimentary phytochemical screening and in vivo exploration of brawny hypoglycemic potency of Aphanamixis Polystachya (Wall.) parker seed extractives
Year: 2024
Type: article
Abstract: Aphanamixis polystachya (Wall.) Parker is a sanative herb with colossal corny convenience. This plant contains a wide range of secondary metabolites, which have been linked to numerous medicinal uses. The current investigation aimed to find the phytochemical components and assess the hypoglycemic impact of n-hexane, chloroform, and methanol extracts of Aphanamixis polystachya seeds. Phytochemical screening was carried out using qualitative analysis. To measure hypoglycemic activity, hyperglycemic lab rats with glucose and STZ were used. All of the extractives contained the phytochemicals flavonoids, terpenoids, and steroids. After 30 minutes of administration, the n-hexane extract showed a drop of 41.44% in blood glucose levels, while the chloroform extract exhibited the most significant reduction, 47.76%, at a dose of 150 mg/g BW. The fascinating discovery is that the methanolic extract, which contained carbohydrates absent in the other extracts, resulted in a 14.92% increase in blood glucose levels within 30 minutes of treatment. Organic seed extracts can prevent hyperglycemia, which will be a significant argument in favor of the Aphanamixis polystachya plant's common uses in traditional medicine to treat diabetes. More research is required to determine the exact mechanism of action, pinpoint the active ingredients, and clarify their structures.
Authors: H. M. Shadid Hossain Snigdha, Ekramul Haque, Tahajul Islam, Shadin Mostakim
Institution: Gopalganj Science and Technology University
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4402984108