Work

Evaluating the duration of antimicrobial therapy for the treatment of orthopedic hardware infections

Year: 2024

Type: article

Abstract: The optimal duration of antimicrobial therapy for orthopedic hardware infections is unclear. We identified 216 patients with orthopedic hardware infections, of whom 42 (19%) later had relapsed infection. Chronic suppressive antimicrobial therapy beyond 12 weeks was not significantly associated with lower odds of relapse.IMPORTANCEThere is debate about how long to continue antibiotics after initial treatment of bone and joint infections when hardware remains in place. This study found no benefit from continuing antibiotics longer than 12 weeks when trying to prevent recurrent infection.

Source: Microbiology Spectrum

DOI: 10.1128/spectrum.01269-24

Authors: Rija Asim, Christian J. Fuchs, Nathan A. Summers

Institution: University of Tennessee Health Science Center

Language: English

Topic: Orthopedic Infections and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500