Work

Heptaelliptoic Acid A, a New Betulinic Acid Saponin from the Leaves of Heptapleurum ellipticum

Year: 2024

Type: article

Abstract: One new 3-O-glycoside of betulinic acid, named heptaelliptoic acid A (1), together with one known betulinic acid analogue (2), and four other compounds (3‒6) were separated by combinatively chromatographic techniques. For the first time, all of the purified compounds (1‒6) were reported from the H. ellipticum species. Their structures were obviously elucidated basing exhaustive and pervasive UV-VIS, FT-IR, HR-MS-ESI, and NMR experiment data. Compounds 2-4 were significantly displayed the in vitro a-glucosidase inhibition (IC50 values of 11.53, 28.75, and 10.90 μM, respectively) better than the acarbose positive drug (IC50 value of 214.50 μM).

Source: Records of Natural Products

DOI: 10.25135/rnp.476.2407.3265