Year: 2024
Type: article
Study design: Case Report
Abstract: BACKGROUND: To report a case of Bilateral Purtscher-like retinopathy associated with DRESS syndrome managed with ocular and systemic treatments. CASE PRESENTATION: A 29-year-old healthy female developed multi-organ (cutaneous, hematologic, renal and hepatic) disfunction and profound vision loss 1 month after Human papillomavirus vaccine injection. At the first presentation, her visual acuity was counting fingers in both eyes. Fundus exam showed remarkable cotton-wool spots, retinal hemorrhages and macular edema. She was diagnosed DRESS syndrome and Purtscher-like retinopathy and treated with intravitreal injection of ranibizumab, systemic steroids anticoagulants, and plasma exchange. The patient finally recovered from this life-threatening condition but left with permanent visual damage. CONCLUSION: Purtscher-like retinopathy could be complicated by DRESS syndrome which is usually considered a type IV hypersensitivity reaction.
Authors: Langxuan Yuan, Yuchen Li, Hanze Zhang, Yucen Hou, Qianyan Kang, Jianqin Lei
Language: English
Topic: Retinal and Optic Conditions
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,190
Awards: G3535145313, G4031077357
OpenAlex ID: W4402995044