Work

Combination Doxycycline and Topical Corticosteroids in the Treatment of Ulcerative Pyoderma Gangrenosum: A Case Report

Year: 2024

Type: article

Abstract: Pyoderma gangrenosum (PG) is a chronic inflammatory neutrophilic dermatosis often presenting as a solitary enlarging painful ulcer with red to violaceous undermined borders. This report delves into the role of doxycycline in the treatment of PG in a 44-year-old male COVID-19 positive patient who has concomitant active tuberculosis infection and end-stage kidney disease, for which both first-line treatments (systemic corticosteroid and cyclosporine) are contraindicated. After three months on doxycycline and topical corticosteroids, there was resolution of the ulcers and no note of recurrence up to three months from completion of the treatment regimen.

Source: Acta Medica Philippina

DOI: 10.47895/amp.v58i17.7462

Authors: Doha Mae Laurisse M. Manalo-Legas, MD, MPM-HSD, Erickah Mary Therese D. Calayag, MD, Eillen Luisa A. Chen, MD

Institutions: Philippine General Hospital, University of the Philippines Manila

Language: English

Topic: Autoimmune and Inflammatory Disorders

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4402996533

FWCI:

Cites: 1

Cited by:

Related to: 10