Work

Discovery of a Highly Potent PROTAC Degrader of p300/CBP Proteins for the Treatment of Enzalutamide-Resistant Prostate Cancer

Year: 2024

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.4c01100

Authors: Mengjun Ma, Mengyao Li, Chengwei Zhang, Zixuan Yang, Xiaoyu Chen, Penghui Lu, Shuangshuang Nie, Siqi Zhang, Shumin Ma, Chong Qin

Institutions: Ocean University of China, Qingdao National Laboratory for Marine Science and Technology

Language: English

Topic: Protein Degradation and Inhibitors

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Taishan Scholar Project of Shandong Province, Key Technology Research and Development Program of Shandong, Natural Science Fund for Distinguished Young Scholars of Shandong Province

Awards: G2179247509, G7567483578, G8957256644

OpenAlex ID: W4402996716

FWCI: 2.083

Cites: 62

Cited by: 18

Related to: 10