Work

GaCl3 ‐Catalyzed [3 + 2]‐Cycloaddition/Esterification Cascade of Donor–Acceptor Cyclopropanes With Salicylaldehydes for the Synthesis of Tetrahydro‐ 4 H‐Furo[3,2‐c]Chromen‐4‐Ones

Year: 2024

Type: article

Abstract: ABSTRACT A GaCl3‐catalyzed [3 + 2]‐cycloaddition/intramolecular esterification cascade of donor–acceptor cyclopropane‐1,1‐diesters with salicylaldehydes has been reported. A wide range of tetrahydro‐4H‐furo[3,2‐c]chromen‐4‐ones have been efficiently delivered in moderate to good yields. Mechanistic studies suggest that the reaction involves the [3 + 2]‐cycloaddition followed by intramolecular esterification to access 4H‐furo[3,2‐c]chromenones.

Source: Journal of Heterocyclic Chemistry

DOI: 10.1002/jhet.4917

Authors: Zhiping Liu, Jie Pang, Lijie Che, Chunfang Gan, Jianguo Cui, Yanmin Huang

Institution: Nanning Normal University

Language: English

Topic: Cyclopropane Reaction Mechanisms

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: Natural Science Foundation of Guangxi Zhuang Autonomous Region, Natural Science Foundation of Guangxi Province

Awards: G282307146, G6290425406