Referral Sources Across Racial and Ethnic Groups at Alzheimer’s Disease Research Centers
Year: 2024
Type: article
Abstract: Background: Despite the need to increase engagement of underrepresented groups (URG) in Alzheimer's disease and related dementias (ADRD) studies, enrollment remains low. Objective: Compare referral sources across racial and ethnic groups among participants enrolled in ADRC studies. Methods: Data for this cross-sectional secondary analysis were extracted from the National Alzheimer's Coordinating Center Uniform Data Set. We performed mixed effects logistic regression models using generalized estimating equations for professional referral versus non-professional referral by racial and ethnic group, adjusted for age, gender, education, visit year, and Clinical Dementia Rating scale (CDR) with a random effect for study site. Results: Included in the analysis were 48,330 participants across 46 ADRCs (mean [SD] age, 71.3 [10.5] years; 20,767 female [57%]; 4,138 Hispanic [8.6%]; 1,392 non-Hispanic Asian [2.9%]; 6,766 non-Hispanic Black [14%] individuals; and 676 individuals [1.4%] of other races. Non-Hispanic Black and Asian participants had lower odds of being referred by a professional contact compared to non-Hispanic White participants (Black: adjusted OR = 0.61, 95% CI = 0.44-0.86, p = 0.005; Asian: adjusted OR = 0.65, 95% CI, p = 0.004). In participants who had completed an MRI, there was no significant difference in referral source across ethnic and racial groups. Conclusions: Further studies are needed to better understand the systemic and structural factors that contribute to differences in referral sources and disparities in recruitment of URG into ADRD studies.
Source: Journal of Alzheimer s Disease
Institutions: Case Western Reserve University, Indiana University School of Medicine, Purdue University West Lafayette, University of Washington, National Alzheimer's Coordinating Center, Rush University Medical Center, University of California Davis Medical Center, University of California, Davis, Indiana University Indianapolis
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Awards: G1024368718, G1048051091, G1069732457, G117713310, G120189231, G1269895679, G1458362881, G1593128567, G1753564228, G1827328465, G1859882300, G2190936067, G2234397790, G2434699210, G253265979, G2622865600, G2675915175, G2742075923, G343469054, G348743638, G3703765782, G3952091757, G415047313, G4186766937, Nevada Exploratory Alzheimer's Disease Research Center (NVEADRC), UAB Alzheimer's Disease Research Center, G504619356, G5640525220, G6245148141, G6652924019, New Mexico Alzheimer's Disease Research Center, G816726602, G8368870138, UCSD Shiley-Marcos Alzheimer's Disease Research Center P30, Joint Estimate Diffusion Imaging (JEDI) for improved Tissue Characterization and Neural Connectivity in Aging and Alzheimer's Disease, University of Kansas Alzheimer's Disease Research Center (KU ADRC), Alzheimer's Disease Research Center, Johns Hopkins Alzheimer's Disease Research Center, Stanford Alzheimer's Disease Research Center, University of Washington Alzheimer's Disease Research Center, Goizueta Alzheimer's Disease Research Center
OpenAlex ID: W4403028416