Year: 2024
Type: conference-paper
Abstract: Bicycle® molecules are suitable vectors for delivering radionuclides to tumours due to their favourable pharmacokinetic properties (specific tumour uptake, rapid penetration and rapid renal clearance).• Due to their rapid clearance from blood circulation and minimal non-specific uptake into healthy tissue (apart from kidneys), they can be used effectively as diagnostic PET agents.• The biodistribution profile of the Bicycle Radionuclide Conjugates (BRCs) can be optimised to maintain high tumour uptake whilst significantly reducing kidney levels.• BRCs emerge as promising agents for a theranostic approach.
Source: European Peptide Symposium (EPS)
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4403036222