Work

Three-component carbonylative Michael addition of aryl bromides using abundant metal-carbonyl under light

Year: 2024

Type: article

Abstract: Carbonyl compounds are widely found in various chemical reactions and natural products . Herein, a light-driven carbonylative cross-coupling reaction of bromobenzene was reported. Co 2 (CO) 8 was used as an abundant solid carbonyl source to synthesize various Michael addition products with high yields. This reaction has broad substrates scope with good functional group tolerance. The mechanism study indicated that the reaction is achieved by the formation of benzoyl radical from homolytic C–Co cleavage under irradiation.

Source: Tetrahedron Green Chem

DOI: 10.1016/j.tgchem.2024.100056

Authors: Shiqian Zhang, Quansheng Mou, Bowen Cao, Tongyu Han, Mingxin Liu

Institutions: State Key Laboratory of Applied Organic Chemistry, Lanzhou University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,800

Funders: National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities