Harnessing gut microbiota for longevity: Insights into mechanisms and genetic manipulation
Year: 2024
Type: article
Abstract: The gut microbiota is pivotal in maintaining health, with most microorganisms being beneficial, except for a few pathogens. Emerging evidence suggests a link between the gut microbiome and aging, hinting at its potential role in longevity. However, understanding the relationship is challenging due to the microbiota's complexity. This perspective summarizes the mechanisms by which gut microbes regulate host lifespan and explores genetic manipulation strategies to promote healthy aging in the elderly.
Source: iMetaOmics.
DOI: 10.1002/imo2.36
Authors: Peng Shi, Simin Xu, Ziling Yang, Liying Wang, Yalun Wu, Ying Li, Zuobin Zhu
Institutions: Xuzhou Medical College, National University of Singapore
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
Awards: G6711803416, G7502563222
OpenAlex ID: W4403065211