Work

Supplementary Figure 2 from NAPRT Silencing in FH-Deficient Renal Cell Carcinoma Confers Therapeutic Vulnerabilities via NAD+ Depletion

Year: 2024

Type: supplementary-materials

Abstract: Hypermethylation of patient derived cell line models and patient samples impacts various cancer related pathways and NAPRT expression.

DOI: 10.1158/1541-7786.27151084

Authors: Katelyn J. Noronha, Karlie N. Lucas, Sateja Paradkar, Joseph Edmonds, Sam Friedman, Matthew A. Murray, Samantha Liu, Dipti P. Sajed, Chana Sachs, Josh Spurrier, Mitch Raponi, Jiayu Liang, Hao Zeng, Ranjini K. Sundaram, Brian Shuch, Juan C. Vasquez, Ranjit S. Bindra

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4403076790

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