Work

Synthesis and characterization of phenethyl isothiocyanate conjugated with magnetic nanoparticles modified by tumor targeting peptide (TTP) using in cancer treatment

Year: 2024

Type: conference-paper

Abstract: Conclusion:In this project, an effective method for synthesizing phenethyl isothiocyanate conjugated with magnetic nanoparticles was developed.In the second step, an anticancer drug (DTX) and a peptide derived from EGF fragments were attached to the MNPs both physically and chemically interaction.The nanoparticles were characterized using TEM, NMR, DLS, FTIR, and TGA.Additionally, peptides were characterized by LC-MS, and their structures were confirmed.The interaction between peptides and MNPs will be studied.

Source: European Peptide Symposium (EPS)

DOI: 10.17952/37eps.2024.p1150

Authors: Sima Alvani Alamdari, Łukasz Janczewski, Justyna Fraczyk

Institution: Lodz University of Technology

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4403099871

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