Work

Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d

Year: 2024

Type: article

Source: Nature Biomedical Engineering

DOI: 10.1038/s41551-024-01256-w

Authors: Namit Chaudhary, Lisa N. Kasiewicz, Alexandra N. Newby, Mariah L. Arral, Saigopalakrishna S. Yerneni, Jilian R. Melamed, Samuel T. LoPresti, Katherine C. Fein, Daria M. Strelkova Petersen, Sushant Kumar, Rahul Purwar, Kathryn A. Whitehead

Institutions: Carnegie Mellon University, Indian Institute of Technology Bombay

Language: English

Topic: RNA Interference and Gene Delivery

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Science Foundation, Foundation for the National Institutes of Health, National Institutes of Health, National Institute of Biomedical Imaging and Bioengineering, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Engineering Smart Protein Coronas to Advance Theraputic mRNA Delivery, Graduate Research Fellowship Program (GRFP), G7416198637, Fate, Function and Genetic Engineering of Breast Milk Cells for Infant Therapy, G9000045356

OpenAlex ID: W4403104998

FWCI: 18.57

Cites: 91

Cited by: 137

Related to: 10