Study protocol TransTAM: Transdiagnostic research into emotional disorders and cognitive-behavioral therapy of the adaptive mind
Year: 2024
Type: article
Study design: Study Protocol
Abstract: BACKGROUND: Emotional disorders such as depression and anxiety disorders share substantial similarities in their etiology and treatment. In recent decades, these commonalities have been increasingly recognized in classification systems and treatment programs crossing diagnostic boundaries. METHODS: To examine the prospective effects of different transdiagnostic markers on relevant treatment outcomes, we plan to track a minimum of N = 200 patients with emotional disorders during their routine course of cognitive behavioral therapy at two German outpatient clinics. We will collect a wide range of transdiagnostic markers, ranging from basic perceptual processes and self-report measures to complex behavioral and neurobiological indicators, before entering therapy. Symptoms and psychopathological processes will be recorded before entering therapy, between the 20th and 24th therapy session, and at the end of therapy. DISCUSSION: Our results could help to identify transdiagnostic markers with high predictive power, but also provide deeper insights into which patient groups with which symptom clusters are less likely to benefit from therapy, and for what reasons. TRIAL REGISTRATION: The trial was preregistered at the German Clinical Trial Register (DRKS-ID: DRKS00031206; 2023-05-09).
Source: BMC Psychiatry
Authors: Andrea Hermann, Christoph Benke, Carlo R. Blecker, Benjamin de Haas, Yifei He, Stefan G. Hofmann, Jona R. Iffland, Johanna Jengert-Stahl, Tilo Kircher, Katrin Leinweber, Marcel Linka, Christoph Mulert, Marie K. Neudert, Ann-Kathrin Noll, Christiane A. Melzig, Winfried Rief, Constantin Rothkopf, Axel Schäfer, Christina V. Schmitter, Verena Schuster, Rudolf Stark, Benjamin Straube, Raphaela I. Zimmer, Lukas Kirchner
Language: English
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Open Access status: gold
Estimated APC paid: $3,190
Award: G3762292575
OpenAlex ID: W4403147070