Work

Chelating drug-induced labile Zn2+ with nanoparticle-encapsulated TPEN at low dose enhances lung cancer chemotherapy through inhibiting ABCB1

Year: 2024

Type: article

Abstract: by nanosized TPEN at low dose enhances lung cancer chemotherapy by inhibiting ABCB1, providing a feasible strategy to overcome chemoresistance in lung cancer.

Source: iScience

DOI: 10.1016/j.isci.2024.111072

Authors: Linlin Wang, Chen Ni, Kaili Zhang, Yuanyuan Yang, Ruoyang Chen, Xiaohan Lou, Yan Yan, Kexin Li, Ya Dong, Xiaohan Yao, Jiajia Wan, Xixi Duan, Fazhan Wang, YongJuan Li, Zhihai Qin

Institutions: Zhengzhou University, First Affiliated Hospital of Zhengzhou University

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,150

Funders: Health Commission of Henan Province, National Natural Science Foundation of China, Science and Technology Department, Henan Province

Awards: G1795090517, G2916448402, G3296949546, G4003023663, G7534475375, G991287329

OpenAlex ID: W4403157472

FWCI: 0.306

Cites: 56

Cited by: 2

Related to: 10