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Comparative Analysis of Mutation in the Buccal Epithelium and Blood in Patients with Lung Cancer and Healthy People

Year: 2024

Type: article

Abstract: Lung cancer is one of the leading causes of cancer death. Finding new methods for the early and accurate diagnosis of lung cancer is critical for effective treatment. We have shown that patients with lung cancer have more mutations in the FLT3, PDGFRA, KDR, PIK3CA, HRAS, FGFR3 genes in the buccal epithelium than people without diagnosed lung cancer. Thus, study of molecular alterations may be used as a method for the accurate diagnosis of lung cancer in the early stages of investigational procedure.

Source: Генетика

DOI: 10.31857/s0016675824050053

Authors: O. V. Serzhantova, A. G. Novikova, A. A. Mikhailov, I. P. Moshurov, A. P. Gureev

Institutions: Voronezh Regional Clinical Oncology Center, Voronezh State University

Language: English

Topic: Cancer Genomics and Diagnostics

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4403169470

FWCI:

Cites: 39

Cited by:

Related to: 10