Optic Nerve Head in Case of Increased Intraocular Pressure, High Intracranial Pressure and Increased Intracranial Pressure with Simultaneous Intraocular Pressure
Year: 2024
Type: article
Abstract: The optic nerve, as part of the central nervous system, is surrounded by meninges and cerebrospinal fluid (CSF). This review discusses the effects of increased intraocular pressure (IOP), elevated intracranial pressure (ICP), and the simultaneous rise in both pressures on the optic nerve head (ONH). Increased IOP, caused by the balance of aqueous humor production and drainage, can lead to glaucomatous optic neuropathy, particularly through mechanical and ischemic damage to the lamina cribrosa. Elevated ICP, characterized by increased CSF pressure, can result in optic nerve edema, impairing axonal transport and blood flow. The complex interactions between IOP and ICP are critical for understanding their combined impact on ONH deformation and glaucomatous damage. It is essential to consider both pressures in clinical evaluations and treatment strategies for optic nerve-related diseases. Recent studies suggest that both IOP and ICP influence the optic nerve head morphology and pathology, highlighting the importance of comprehensive management approaches. Further research is needed to elucidate the intricate dynamics of IOP and ICP in the pathogenesis of optic nerve diseases.
DOI: 10.37783/crj-0451
Authors: Kıvanç GÜNGÖR, Sevim Ayça SEYYAR
Language: English
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4403170026