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The MdERF61-mdm-miR397b- MdLAC7b module regulates apple resistance to Fusarium solani via lignin biosynthesis

Year: 2024
Type: article
Abstract: Apple replant disease (ARD) is a worldwide problem that threatens the industry. However, the genetic mechanism underlying plant disease resistance against ARD remains unclear. In this study, a negative regulatory microRNA in Malus domestica, mdm-miR397b, and its direct target MdLAC7b (Laccase) was selected for examination based on our previous small RNA and degradome sequencing results. Overexpressing the mdm-miR397b-MdLAC7b module altered the lignin deposition and jasmonic acid contents in apple roots, which also led to increased resistance to Fusarium solani. Additionally, Y1H library screening using mdm-miR397b promoter recombinants identified a transcription factor, MdERF61, that represses mdm-miR397b transcriptional activity by directly binding to 2 GCC-boxes in the mdm-miR397b promoter. In summary, our results suggest that the MdERF61-mdm-miR397b-MdLAC7b module plays a crucial role in apple resistance to F. solani and offers insights for enhancing plant resistance to soil-borne diseases in apples.
DOI: 10.1093/plphys/kiae518
Authors: Zhe Zhou, Haiqing Zhang, Haiqing Zhang, Jia-Long Yao, Qiming Gao, Yarong Wang, Zhenzhen Liu, Yaru Zhang, Yi Tian, Zhenli Yan, Yanmin Zhu, Hengtao Zhang, Hengtao Zhang
Institutions: Zhengzhou Fruit Research Institute, Chinese Academy of Agricultural Sciences, Plant & Food Research, Hebei Agricultural University, Agricultural Research Service, United States Department of Agriculture, Tree Fruit Research Laboratory
Language: English
Subfield: Plant Science
Open Access status: hybrid
Estimated APC paid: $4,101
OpenAlex ID: W4403177458
FWCI: 4.239
Cites: 76
Cited by: 19
Related to: 10