Work

Dehydrogenative Coupling Reactions with Guanidino‐Functionalized Aromatics

Year: 2024

Type: article

Abstract: Dehydrogenative coupling (DC) reactions are of importance for the construction of new carbon-element bonds in synthetic organic chemistry. In this work, we report on the synthesis and characterization of several redox-active guanidino-functionalized aromatic molecules (GFAs) for use in DC (C-C and C-O) reactions. In a systematic approach, we first characterize the new DC reagents in all relevant redox and protonation states, and compare their performance in competitive test proton-coupled electron transfer (PCET) reactions. Then, their use in four different DC reactions with different mechanisms is evaluated.

Source: Chemistry - A European Journal

DOI: 10.1002/chem.202402917

Authors: Petra Walter, Maximilian Schulz, Olaf Hübner, Andrei Poddelskii, Elisabeth Kaifer, Hans‐Jörg Himmel

Institution: Heidelberg University

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,640

Funder: Deutsche Forschungsgemeinschaft