Work

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) in a 32-Year-Old Male Presenting With a Transient Ischemic Attack (TIA)

Year: 2024

Type: article

Abstract: This case report describes a 32-year-old male with a familial history of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), presenting with right-sided weakness and visual disturbances. The symptoms, consistent with a transient ischemic attack (TIA), resolved spontaneously. Subsequent evaluation, including MRI brain imaging, revealed a high T2 signal in subcortical white matter in the frontal and parietal lobes, consistent with CADASIL. Positive NOTCH3 testing confirmed the diagnosis, leading to the initiation of antiplatelet and statin therapy under the care of both stroke and neurology teams.

Source: Cureus

DOI: 10.7759/cureus.70970

Authors: Rabail Karim, Munzir Malik, Hamza Cheema, Abdul Aziz, Rimsha Khan

Institutions: Walton Centre, Wrexham Maelor Hospital

Language: English

Topic: Cerebrovascular and genetic disorders

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403201256