Work

Role of KIM-1 in early diagnosis of contrast-induced nephropathy following invasive cardiac procedure: A systematic review

Year: 2024

Type: review

Abstract: This systematic review aims to provide a comprehensive analysis of the diagnostic efficacy of KIM-1 in CI-AKI. We evaluated its potential as a robust biomarker for the early identification and prediction of AKI progression. Methodology To assess KIM-1 as a biomarker for CI-AKI, relevant databases were searched. Inclusion criteria comprised studies measuring KIM-1 levels in patients undergoing cardiac procedures with contrast media. And data were extracted. Methodological quality and bias were evaluated using Quadas-2 tool. Conclusion KIM-1 shows promise as a biomarker for renal injury. Its upregulation, correlation with injury severity, and involvement in tissue repair support its clinical relevance. Prospero Registration Number CRD42023431419

Source: Clinical Epidemiology and Global Health

DOI: 10.1016/j.cegh.2024.101765

Authors: Mantasha Shuaib, Md Masoom, Mohd Ashif Khan

Institution: Jamia Hamdard

Language: English

Topic: Acute Kidney Injury Research

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,200