Work

Antiangiogenic effects in the modulation of inflammatory pathways. A comprehensive analysis of potential therapeutic substances

Year: 2024

Type: article

Abstract: Based on current knowledge antiangiogenic compounds are utilized in the treatment of inflammatory-depended diseases such as cancer. It has been shown that these compounds can simultaneously block several signalling pathways regulating angiogenesis. The visualization of fluorescently labelled F-actin and VE-cadherin was allowed to demonstrate that the reorganization of the cell cytoskeleton disrupts cellular processes and consequently inhibits angiogenesis.

Source: Medical Research Journal

DOI: 10.5603/mrj.101851

Authors: Klaudia Piekarska, Dominika Spyt, Klaudia Bonowicz, Dominika Jerka, Alina Grzanka, Maciej Gagat

Institutions: Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz

Language: English

Topic: Angiogenesis and VEGF in Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4403220897

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