Combined Effects of Mechanical Ventilation and Postural Drainage in Acute Respiratory Distress Syndrome
Year: 2024
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Background: Acute Respiratory Distress Syndrome (ARDS) is a severe condition impacting lung function, often requiring mechanical ventilation. Postural drainage may improve oxygenation and airway clearance in ARDS patients, particularly in those with burn injuries and inhalation trauma.Objective: This study aimed to evaluate the combined effects of mechanical ventilation and postural drainage on oxygen saturation and airway clearance in burn patients with ARDS.Methods: A randomized controlled trial was conducted with 50 burn patients, aged 20-50, admitted to the ICU. Patients were divided into two groups: Group A received postural drainage with mechanical ventilation, and Group B received only mechanical ventilation. Data were collected daily using the APACHE II scale. FiO2, PO2, pH, and HCO3 levels were measured pre- and post-treatment. Data were analyzed using SPSS version 25.Results: The post-treatment FiO2 in Group A increased from 48.80 ± 18.92% to 85.40 ± 13.69%, while PO2 increased from 66.40 ± 17.22 mmHg to 77.40 ± 15.08 mmHg. Statistically significant improvements were observed in oxygenation (p < 0.05), with no significant changes in pH and PCO2.Conclusion: Postural drainage combined with mechanical ventilation significantly improves oxygenation in burn patients with ARDS.
Authors: Sidra Afzal, Mishal Shamsi, Sara Abroo, Muhammad Ahmed, Noor UL HUDA, Muhammad Ali Haider
Institutions: Riphah International University, Hajvery University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4403245577