Performance of serum amyloid A and C reactive protein for disease control assessment in familial Mediterranean fever
Year: 2024
Type: article
Abstract: Familial Mediterranean fever (FMF) is a monogenic autoinflammatory disease responsible for periodic inflammatory flares. The most critical complication of FMF is AA amyloidosis.1 It is caused by the deposition of serum amyloid A (SAA) proteins in the organs due to repeated or chronic high levels of SAA.2 European recommendations for the treatment of FMF suggest that C-reactive protein (CRP) and SAA levels should be monitored.2,3 The assessment of disease control relies on both inflammatory markers and declared number of flares, which can be subjective.
Institutions: Inserm, Sorbonne Université, Assistance Publique – Hôpitaux de Paris, Centre de Référence des Maladies Autoinflammatoires et des Amyloses, Hôpital André Mignot, Centre de Recherche Saint-Antoine, Centre Hospitalier de Versailles, Hôpital Tenon, Hospices Civils de Lyon, University of Liège, Centre Hospitalier Universitaire de Liège, Lyon 1 Université, École Normale Supérieure de Lyon, Centre National de la Recherche Scientifique, Centre International de Recherche en Infectiologie
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,000
OpenAlex ID: W4403265367