Work

Zinc and gallium doped borate bioactive glasses influence in-vitro angiogenesis: New evidence in cell co-culture studies

Year: 2024

Type: article

Abstract: Borate bioactive glasses doped with 1 mol% ZnO or Ga 2 O 3 were produced by melt-quenching. The cytocompatibility of fibroblast and endothelial cells in response to glass extracts was assessed. The angiogenic potential was examined through fibroblast-derived vascular endothelial growth factor secretion and tubular formation analysis in an indirect co-culture of fibroblast and endothelial cells. The results confirm that Zn and Ga ion-releasing bioactive glasses are attractive biomaterials with angiogenic properties.

Source: Materials Letters

DOI: 10.1016/j.matlet.2024.137529

Authors: Nurshen Mutlu, Marcela Arango-Ospina, Rainer Detsch, Dušan Galusek, Aldo R. Boccaccini

Institutions: Friedrich-Alexander-Universität Erlangen-Nürnberg, Trencianska Univerzita Alexandra Dubceka V Trencine

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,540