Work

Thin and in situ melanomas of unfavorable prognosis: A retrospective observational analysis of local recurrence, metastasis, and death in early-stage disease

Year: 2024

Type: article

Abstract: Thin and in situ melanomas of unfavorable prognosis: A retrospective observational analysis of local recurrence, metastasis, and death in early-stage disease To the Editor: Rates of melanoma in situ (MIS) and thin melanoma (TM, defined as Breslow thickness #1.0 mm) are increasing.A recent evaluation of MIS revealed that the 15-year melanoma-specific survival was relatively high at 98.4%, 1 raising concern for potential overdiagnosis. 2 However, little data exists regarding the characteristics and potential for mortality in this population.We examined Brazilian and US cohorts diagnosed with MIS or TM from 1997 to 2020.Our low-risk cohort excluded any patients with poor prognostic Fig 1. Patient inclusion flowchart.

Source: Journal of the American Academy of Dermatology

DOI: 10.1016/j.jaad.2024.09.057

Authors: Joao Renato V. Gontijo, Jacob H. Nelson, Kyra Diehl, Veselina B. Korcheva, Flavia Vasques Bittencourt, Sancy A. Leachman

Institutions: Universidade Federal de Minas Gerais, Oregon Health & Science University, Mater Dei Hospital, Providence Portland Medical Center

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,200