Work

Wnt-Signaltransduktion in motilen Zilien und Geißeln

Year: 2024

Type: article

Abstract: Motile cilia are essential for many biological processes, including mucus transport in the human airway or in the male and female reproductive system. Unraveling their biogenesis and mechanisms regulating their coordinate beating motion are of medical interest to understand ciliopathies. We recently discovered that cilia are Wnt signaling organelles. Here, we discuss the intraciliary Wnt/GSK3 signaling axis that is required for cilia biogenesis and for motile cilia function.

Source: BIOspektrum

DOI: 10.1007/s12268-024-2298-3

Authors: Carina Seidl, Christof Niehrs

Institutions: Institute of Molecular Biotechnology, Austrian Academy of Sciences, Vienna Biocenter, German Cancer Research Center, DKFZ-ZMBH Alliance, Institute of Molecular Biology

Language: English

Topic: Genetic and Kidney Cyst Diseases

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,090

OpenAlex ID: W4403295066

FWCI:

Cites: 11

Cited by:

Related to: 10