Year: 2024
Type: article
Abstract: Chaetomium thermophilum is an eukaryotic thermophilic fungus that holds great potential for broad biochemical and biotechnological applications. We have developed a tool box for its genetic manipulation rendering this organism amenable as resource for structural biology. Here, we elucidate these approaches as a foundation for affinity purification of thermostable macromolecular complexes, like nucleoporin complexes and pre-ribosomal particles.
Source: BIOspektrum
Authors: Nikola Kellner, Ed Hurt
Institution: Heidelberg University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,090
OpenAlex ID: W4403295091